Often combined with glucosamine, MSM (methylsulfonylmethane) helps support cartilage health Restores cartilage flexibility Makes cells more permeable, allowing nutrients to pass through the cell walls more easily while efficiently transporting metabolic waste out of the cells Often combined with glucosamine, MSM (methylsulfonylmethane) also helps support cartilage and restore its flexibility. Its ability to make the cells more permeable means nutrients pass through the cell walls more easily while metabolic waste is efficiently transported out of the cell. An organic sulfur compound, MSM is also very helpful for the skin, providing hydration and structural support for a more youthful appearance. (MSM works in synergy with vitamin C to build collagen.)